Inactivation of human gamma interferon by Pseudomonas aeruginosa proteases: elastase augments the effects of alkaline protease despite the presence of alpha 2-macroglobulin.

Pseudomonas aeruginosa alkaline protease (AP) has recently been shown to produce limited proteolysis of human gamma interferon (IFN-gamma) and thereby destroy the antiviral and macrophage-activating activities of the lymphokine. In the present study we describe some of the characteristics of Pseudom...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Horvat, R. T., Clabaugh, M., Duval-Jobe, C., Parmely, M. J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1989
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313337/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2470675/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.6.1668-1674.1989
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