Inactivation of human factor VIII by activated protein C. Cofactor activity of protein S and protective effect of von Willebrand factor.

Activated protein C (APC) acts as a potent anticoagulant enzyme by inactivating Factor V and Factor VIII. In this study, protein S was shown to increase the inactivation of purified Factor VIII by APC ninefold. The reaction rate was saturated with respect to the concentration of protein S when prote...

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Bibliografski detalji
Glavni autori: Koedam, J A, Meijers, J C, Sixma, J J, Bouma, B N
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC442674/
https://ncbi.nlm.nih.gov/pubmed/2971673
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