αβ T-cell receptors from multiple sclerosis brain lesions show MAIT cell–related features

OBJECTIVES: To characterize phenotypes of T cells that accumulated in multiple sclerosis (MS) lesions, to compare the lesional T-cell receptor (TCR) repertoire of T-cell subsets to peripheral blood, and to identify paired α and β chains from single CD8(+) T cells from an index patient who we followe...

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Publicado no:Neurol Neuroimmunol Neuroinflamm
Main Authors: Held, Kathrin, Bhonsle-Deeng, Latika, Siewert, Katherina, Sato, Wakiro, Beltrán, Eduardo, Schmidt, Stephan, Rühl, Geraldine, Ng, Judy K.M., Engerer, Peter, Moser, Markus, Klinkert, Wolfgang E.F., Babbe, Holger, Misgeld, Thomas, Wekerle, Hartmut, Laplaud, David-Axel, Hohlfeld, Reinhard, Dornmair, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426681/
https://ncbi.nlm.nih.gov/pubmed/25977934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000107
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