Premature termination of variable gene rearrangement in B lymphocytes from X-linked agammaglobulinemia.

X-linked agammaglobulinemia (XLA) results from failure of B lymphocyte development. Immature B cells from a patient with XLA were found to produce truncated mu and delta immunoglobulin H chains encoded by D-JH-C (mu delta). The 5' terminal sequence of cDNA encoding the H chains is composed of D-JH w...

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izdano v:	J Clin Invest
Principais autores:	Schwaber, J, Chen, R H
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 1988
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442655/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2838527/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113550
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