Premature termination of variable gene rearrangement in B lymphocytes from X-linked agammaglobulinemia.
X-linked agammaglobulinemia (XLA) results from failure of B lymphocyte development. Immature B cells from a patient with XLA were found to produce truncated mu and delta immunoglobulin H chains encoded by D-JH-C (mu delta). The 5' terminal sequence of cDNA encoding the H chains is composed of D-JH w...
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| Publicado no: | J Clin Invest |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442655/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2838527/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113550 |
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