Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote regulatory T-cell differentiation

Peripheral induction of regulatory T (Treg) cells provides essential protection from inappropriate immune responses. CD4(+) T cells that lack endogenous miRNAs are impaired to differentiate into Treg cells, but the relevant miRNAs are unknown. We performed an overexpression screen with T-cell-expres...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:EMBO J
Hlavní autoři: Warth, Sebastian C, Hoefig, Kai P, Hiekel, Anian, Schallenberg, Sonja, Jovanovic, Ksenija, Klein, Ludger, Kretschmer, Karsten, Ansel, K Mark, Heissmeyer, Vigo
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426480/
https://ncbi.nlm.nih.gov/pubmed/25712478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489589
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky