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Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote regulatory T-cell differentiation
Peripheral induction of regulatory T (Treg) cells provides essential protection from inappropriate immune responses. CD4(+) T cells that lack endogenous miRNAs are impaired to differentiate into Treg cells, but the relevant miRNAs are unknown. We performed an overexpression screen with T-cell-expres...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BlackWell Publishing Ltd
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4426480/ https://ncbi.nlm.nih.gov/pubmed/25712478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489589 |
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