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Formation of factor Va by atherosclerotic rabbit aorta mediates factor Xa-catalyzed prothrombin activation.

Vascular cell procoagulant activity may be important in the pathogenesis of atherosclerosis. In previous studies, we described the ability of the atherogenic metabolite homocysteine to activate endothelial cell Factor V, a key coagulation cofactor for thrombin generation. The present study was desig...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Rodgers, G M, Kane, W H, Pitas, R E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442643/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3164315/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113538
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