Formation of factor Va by atherosclerotic rabbit aorta mediates factor Xa-catalyzed prothrombin activation.

Vascular cell procoagulant activity may be important in the pathogenesis of atherosclerosis. In previous studies, we described the ability of the atherogenic metabolite homocysteine to activate endothelial cell Factor V, a key coagulation cofactor for thrombin generation. The present study was desig...

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Опубликовано в::	J Clin Invest
Главные авторы:	Rodgers, G M, Kane, W H, Pitas, R E
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Clinical Investigation 1988
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3164315/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113538
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