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Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell

How cells maintain nuclear shape and position against various intracellular and extracellular forces is not well understood, although defects in nuclear mechanical homeostasis are associated with a variety of human diseases. We estimated the force required to displace and deform the nucleus in adher...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Neelam, Srujana, Chancellor, T. J., Li, Yuan, Nickerson, Jeffrey A., Roux, Kyle J., Dickinson, Richard B., Lele, Tanmay P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426403/
https://ncbi.nlm.nih.gov/pubmed/25901323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502111112
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