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Pathway-Based Factor Analysis of Gene Expression Data Produces Highly Heritable Phenotypes That Associate with Age
Statistical factor analysis methods have previously been used to remove noise components from high-dimensional data prior to genetic association mapping and, in a guided fashion, to summarize biologically relevant sources of variation. Here, we show how the derived factors summarizing pathway expres...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | G3 (Bethesda) |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Genetics Society of America
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4426370/ https://ncbi.nlm.nih.gov/pubmed/25758824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.114.011411 |
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