Myocardial infarction activates CCR2(+) hematopoietic stem and progenitor cells

Following myocardial infarction (MI), myeloid cells derived from the hematopoietic system drive a sharp increase in systemic leukocyte levels that correlate closely with mortality. The origin of these myeloid cells, and the response of hematopoietic stem and progenitor cells (HSPCs) to MI, however,...

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Published in:Cell Stem Cell
Main Authors: Dutta, Partha, Sager, Hendrik B., Stengel, Kristy R., Naxerova, Kamila, Courties, Gabriel, Saez, Borja, Silberstein, Lev, Heidt, Timo, Sebas, Matthew, Sun, Yuan, Wojtkiewicz, Gregory, Feruglio, Paolo Fumene, King, Kevin, Baker, Joshua N., van der Laan, Anja M., Borodovsky, Anna, Fitzgerald, Kevin, Hulsmans, Maarten, Hoyer, Friedrich, Iwamoto, Yoshiko, Vinegoni, Claudio, Brown, Dennis, Di Carli, Marcelo, Libby, Peter, Hiebert, Scott, Scadden, David, Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426344/
https://ncbi.nlm.nih.gov/pubmed/25957903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.04.008
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