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G Protein-Coupled Receptor Signaling to Kir channels in Xenopus Oocytes

Kir3 (or GIRK) channels have been known for nearly three decades to be activated by direct interactions with the βγ subunits of heterotrimeric G (Gαβγ) proteins in a membrane-delimited manner. Gα also interacts with GIRK channels and since PTX-sensitive Gα subunits show higher affinity of interactio...

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Detalhes bibliográficos
Publicado no:Curr Pharm Biotechnol
Main Authors: Hatcher-Solis, Candice, Fribourg, Miguel, Spyridaki, Katerina, Younkin, Jason, Ellaithy, Amr, Xiang, Guoqing, Liapakis, George, Gonzalez-Maeso, Javier, Zhang, Hailin, Cui, Meng, Logothetis, Diomedes E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426293/
https://ncbi.nlm.nih.gov/pubmed/25374032
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