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G Protein-Coupled Receptor Signaling to Kir channels in Xenopus Oocytes

Kir3 (or GIRK) channels have been known for nearly three decades to be activated by direct interactions with the βγ subunits of heterotrimeric G (Gαβγ) proteins in a membrane-delimited manner. Gα also interacts with GIRK channels and since PTX-sensitive Gα subunits show higher affinity of interactio...

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Dettagli Bibliografici
Pubblicato in:Curr Pharm Biotechnol
Autori principali: Hatcher-Solis, Candice, Fribourg, Miguel, Spyridaki, Katerina, Younkin, Jason, Ellaithy, Amr, Xiang, Guoqing, Liapakis, George, Gonzalez-Maeso, Javier, Zhang, Hailin, Cui, Meng, Logothetis, Diomedes E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426293/
https://ncbi.nlm.nih.gov/pubmed/25374032
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