G Protein-Coupled Receptor Signaling to Kir channels in Xenopus Oocytes

Kir3 (or GIRK) channels have been known for nearly three decades to be activated by direct interactions with the βγ subunits of heterotrimeric G (Gαβγ) proteins in a membrane-delimited manner. Gα also interacts with GIRK channels and since PTX-sensitive Gα subunits show higher affinity of interactio...

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Publicado en:Curr Pharm Biotechnol
Autores principales: Hatcher-Solis, Candice, Fribourg, Miguel, Spyridaki, Katerina, Younkin, Jason, Ellaithy, Amr, Xiang, Guoqing, Liapakis, George, Gonzalez-Maeso, Javier, Zhang, Hailin, Cui, Meng, Logothetis, Diomedes E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426293/
https://ncbi.nlm.nih.gov/pubmed/25374032
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