Elastase regulates the synthesis of its inhibitor, alpha 1-proteinase inhibitor, and exaggerates the defect in homozygous PiZZ alpha 1 PI deficiency.
The net balance of neutrophil elastase, an enzyme that degrades many components of the extracellular matrix, and its inhibitor, alpha-1-proteinase inhibitor (alpha 1 PI), is thought to be a critical determinant in the development of destructive lung disease, especially in individuals with homozygous...
-д хадгалсан:
| -д хэвлэсэн: | J Clin Invest |
|---|---|
| Үндсэн зохиолчид: | , , |
| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
American Society for Clinical Investigation
1988
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| Нөхцлүүд: | |
| Онлайн хандалт: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3260245/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113519 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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