Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes.

Clostridium difficile, a common enteric pathogen, mediates tissue damage and intestinal fluid secretion by release of two protein exotoxins: toxin A, an enterotoxin, and toxin B, a cytotoxin. Because toxin A elicits an intense inflammatory reaction in vivo, we studied the effects of highly purified...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Pothoulakis, C, Sullivan, R, Melnick, D A, Triadafilopoulos, G, Gadenne, A S, Meshulam, T, LaMont, J T
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1988
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442619/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2838520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113514
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