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Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes.

Clostridium difficile, a common enteric pathogen, mediates tissue damage and intestinal fluid secretion by release of two protein exotoxins: toxin A, an enterotoxin, and toxin B, a cytotoxin. Because toxin A elicits an intense inflammatory reaction in vivo, we studied the effects of highly purified...

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Detalhes bibliográficos
Main Authors: Pothoulakis, C, Sullivan, R, Melnick, D A, Triadafilopoulos, G, Gadenne, A S, Meshulam, T, LaMont, J T
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC442619/
https://ncbi.nlm.nih.gov/pubmed/2838520
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