Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer’s pathophysiology and susceptibility

BACKGROUND: Alzheimer’s disease is a neurodegenerative disorder in which extracellular deposition of β-amyloid (Aβ) oligomers causes synaptic injury resulting in early memory loss, altered homeostasis, accumulation of hyperphosphorylated tau and cell death. Since proteins in the SNAP (Soluble N-ethy...

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Détails bibliographiques
Publié dans:Mol Neurodegener
Auteurs principaux: Sevlever, Daniel, Zou, Fanggeng, Ma, Li, Carrasquillo, Sebastian, Crump, Michael G, Culley, Oliver J, Hunter, Talisha A, Bisceglio, Gina D, Younkin, Linda, Allen, Mariet, Carrasquillo, Minerva M, Sando, Sigrid B, Aasly, Jan O, Dickson, Dennis W, Graff-Radford, Neill R, Petersen, Ronald C, Belbin, Olivia
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426163/
https://ncbi.nlm.nih.gov/pubmed/25881291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0015-x
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