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VERY LOW-DOSE (FEMTOMOLAR) 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD) DISRUPTS STEROIDOGENIC ENZYME mRNAs AND STEROID SECRETION BY HUMAN LUTEINIZING GRANULOSA CELLS
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is the most toxic congener of the polyhalogenated aromatic hydrocarbons (PAH), which causes anatomical abnormalities and developmental defects, impairs ovulation and reduces fertility. TCDD’s endocrine-disrupting effects are, in part, caused by a direct act...
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| Veröffentlicht in: | Reprod Toxicol |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4426074/ https://ncbi.nlm.nih.gov/pubmed/25697571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2015.02.003 |
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