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VERY LOW-DOSE (FEMTOMOLAR) 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD) DISRUPTS STEROIDOGENIC ENZYME mRNAs AND STEROID SECRETION BY HUMAN LUTEINIZING GRANULOSA CELLS

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is the most toxic congener of the polyhalogenated aromatic hydrocarbons (PAH), which causes anatomical abnormalities and developmental defects, impairs ovulation and reduces fertility. TCDD’s endocrine-disrupting effects are, in part, caused by a direct act...

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Publicat a:Reprod Toxicol
Autors principals: Baldridge, MG, Marks, GT, Rawlins, RG, Hutz, RJ
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426074/
https://ncbi.nlm.nih.gov/pubmed/25697571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2015.02.003
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