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Solution Structure of the Atg1 Complex: Implications for the Architecture of the Phagophore Assembly Site
The biogenesis of autophagosomes commences at the phagophore assembly site (PAS), a protein-vesicle ultrastructure that is organized by the Atg1 complex. The Atg1 complex consists of the Atg1 protein kinase, the intrinsically disordered region-rich Atg13, and the dimeric double crescent-shaped Atg17...
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| Publicado en: | Structure |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4426065/ https://ncbi.nlm.nih.gov/pubmed/25817386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.02.012 |
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