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Determining Atg protein stoichiometry at the phagophore assembly site by fluorescence microscopy

In eukaryotic cells, autophagy is a lysosomal/vacuolar degradative pathway necessary for the turnover of different macromolecules. Autophagy is under precise regulation, not only qualitatively but also quantitatively, and excess or reduced levels of autophagy may lead to various human diseases. In y...

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Bibliographic Details
Main Authors: Geng, Jiefei, Klionsky, Daniel J.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841983/
https://ncbi.nlm.nih.gov/pubmed/20131413
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