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Ascorbic acid improves pluripotency of human parthenogenetic embryonic stem cells through modifying imprinted gene expression in the Dlk1-Dio3 region

INTRODUCTION: Human parthenogenetic embryonic stem cells (hpESCs) are generated from artificially activated oocytes, however, the issue of whether hpESCs have equivalent differentiation ability to human fertilized embryonic stem cells remains controversial. METHODS: hpESCs were injected into male se...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Yu, Yang, Gao, Qian, Zhao, Hong-cui, Li, Rong, Gao, Jiang-man, Ding, Ting, Bao, Si-yu, Zhao, Yue, Sun, Xiao-fang, Fan, Yong, Qiao, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425892/
https://ncbi.nlm.nih.gov/pubmed/25879223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0054-9
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