Ascorbic acid improves pluripotency of human parthenogenetic embryonic stem cells through modifying imprinted gene expression in the Dlk1-Dio3 region

INTRODUCTION: Human parthenogenetic embryonic stem cells (hpESCs) are generated from artificially activated oocytes, however, the issue of whether hpESCs have equivalent differentiation ability to human fertilized embryonic stem cells remains controversial. METHODS: hpESCs were injected into male se...

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Publicado en:Stem Cell Res Ther
Autores principales: Yu, Yang, Gao, Qian, Zhao, Hong-cui, Li, Rong, Gao, Jiang-man, Ding, Ting, Bao, Si-yu, Zhao, Yue, Sun, Xiao-fang, Fan, Yong, Qiao, Jie
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425892/
https://ncbi.nlm.nih.gov/pubmed/25879223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0054-9
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