Treatment of established left ventricular hypertrophy with fibroblast growth factor receptor blockade in an animal model of CKD

BACKGROUND: Activation of fibroblast growth factor receptor (FGFR)-dependent signalling by FGF23 may contribute to the complex pathogenesis of left ventricular hypertrophy (LVH) in chronic kidney disease (CKD). Pan FGFR blockade by PD173074 prevented development of LVH in the 5/6 nephrectomy rat mod...

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Vydáno v:Nephrol Dial Transplant
Hlavní autoři: Di Marco, Giovana Seno, Reuter, Stefan, Kentrup, Dominik, Grabner, Alexander, Amaral, Ansel Philip, Fobker, Manfred, Stypmann, Jörg, Pavenstädt, Hermann, Wolf, Myles, Faul, Christian, Brand, Marcus
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425841/
https://ncbi.nlm.nih.gov/pubmed/24875663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfu190
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