Treatment of established left ventricular hypertrophy with fibroblast growth factor receptor blockade in an animal model of CKD

BACKGROUND: Activation of fibroblast growth factor receptor (FGFR)-dependent signalling by FGF23 may contribute to the complex pathogenesis of left ventricular hypertrophy (LVH) in chronic kidney disease (CKD). Pan FGFR blockade by PD173074 prevented development of LVH in the 5/6 nephrectomy rat mod...

Full description

Saved in:
Bibliographic Details
Published in:Nephrol Dial Transplant
Main Authors: Di Marco, Giovana Seno, Reuter, Stefan, Kentrup, Dominik, Grabner, Alexander, Amaral, Ansel Philip, Fobker, Manfred, Stypmann, Jörg, Pavenstädt, Hermann, Wolf, Myles, Faul, Christian, Brand, Marcus
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425841/
https://ncbi.nlm.nih.gov/pubmed/24875663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfu190
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items