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Treatment of established left ventricular hypertrophy with fibroblast growth factor receptor blockade in an animal model of CKD
BACKGROUND: Activation of fibroblast growth factor receptor (FGFR)-dependent signalling by FGF23 may contribute to the complex pathogenesis of left ventricular hypertrophy (LVH) in chronic kidney disease (CKD). Pan FGFR blockade by PD173074 prevented development of LVH in the 5/6 nephrectomy rat mod...
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| Udgivet i: | Nephrol Dial Transplant |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4425841/ https://ncbi.nlm.nih.gov/pubmed/24875663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfu190 |
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