An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells

BACKGROUND: Multidrug resistant cancer cells are hard to eradicate for the inefficacy of conventional anticancer drugs. Besides escaping the cytotoxic effects of chemotherapy, they also bypass the pro-immunogenic effects induced by anticancer drugs: indeed they are not well recognized by host dendri...

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Vydáno v:PLoS One
Hlavní autoři: Campia, Ivana, Buondonno, Ilaria, Castella, Barbara, Rolando, Barbara, Kopecka, Joanna, Gazzano, Elena, Ghigo, Dario, Riganti, Chiara
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425697/
https://ncbi.nlm.nih.gov/pubmed/25955018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126159
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