Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition

BACKGROUND: The activity of P-glycoprotein (Pgp) and multidrug resistance related protein 1 (MRP1), two membrane transporters involved in multidrug resistance of colon cancer, is increased by high amounts of cholesterol in plasma membrane and detergent resistant membranes (DRMs). It has never been i...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Mol Cancer
Autors principals: Gelsomino, Giada, Corsetto, Paola A, Campia, Ivana, Montorfano, Gigliola, Kopecka, Joanna, Castella, Barbara, Gazzano, Elena, Ghigo, Dario, Rizzo, Angela M, Riganti, Chiara
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225767/
https://ncbi.nlm.nih.gov/pubmed/24225025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-137
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars