Loss of Expression of Reprimo, a p53-induced Cell Cycle Arrest Gene, Correlates with Invasive Stage of Tumor Progression and p73 Expression in Gastric Cancer

Reprimo (RPRM), a downstream effector of p53-induced cell cycle arrest at G2/M, has been proposed as a putative tumor suppressor gene (TSG) and as a potential biomarker for non-invasive detection of gastric cancer (GC). The aim of this study was to evaluate the epigenetic silencing of RPRM gene by p...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Saavedra, Kathleen, Valbuena, José, Olivares, Wilda, Marchant, María José, Rodríguez, Andrés, Torres-Estay, Verónica, Carrasco-Avino, Gonzalo, Guzmán, Leda, Aguayo, Francisco, Roa, Juan Carlos, Corvalán, Alejandro H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425545/
https://ncbi.nlm.nih.gov/pubmed/25954972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125834
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