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The Reprimo-Like Gene Is an Epigenetic-Mediated Tumor Suppressor and a Candidate Biomarker for the Non-Invasive Detection of Gastric Cancer

Reprimo-like (RPRML) is an uncharacterized member of the Reprimo gene family. Here, we evaluated the role of RPRML and whether its regulation by DNA methylation is a potential non-invasive biomarker of gastric cancer. RPRML expression was evaluated by immunohistochemistry in 90 patients with gastric...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Alarcón, María Alejandra, Olivares, Wilda, Córdova-Delgado, Miguel, Muñoz-Medel, Matías, de Mayo, Tomas, Carrasco-Aviño, Gonzalo, Wichmann, Ignacio, Landeros, Natalia, Amigo, Julio, Norero, Enrique, Villarroel-Espíndola, Franz, Riquelme, Arnoldo, Garrido, Marcelo, Owen, Gareth I., Corvalán, Alejandro H.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763358/
https://ncbi.nlm.nih.gov/pubmed/33322837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249472
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