Canine Mammary Tumours Are Affected by Frequent Copy Number Aberrations, including Amplification of MYC and Loss of PTEN

BACKGROUND: Copy number aberrations frequently occur during the development of many cancers. Such events affect dosage of involved genes and may cause further genomic instability and progression of cancer. In this survey, canine SNP microarrays were used to study 117 canine mammary tumours from 69 d...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Borge, Kaja S., Nord, Silje, Van Loo, Peter, Lingjærde, Ole C., Gunnes, Gjermund, Alnæs, Grethe I. G., Solvang, Hiroko K., Lüders, Torben, Kristensen, Vessela N., Børresen-Dale, Anne-Lise, Lingaas, Frode
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425491/
https://ncbi.nlm.nih.gov/pubmed/25955013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126371
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