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Epigallocatechin 3-Gallate Ameliorates Bile Duct Ligation Induced Liver Injury in Mice by Modulation of Mitochondrial Oxidative Stress and Inflammation

Cholestatic liver fibrosis was achieved by bile duct ligation (BDL) in mice. Liver injury associated with BDL for 15 days included significant reactive oxygen/nitrogen species generation, liver inflammation, cell death and fibrosis. Administration of Epigallocatechin 3-Gallate (EGCG) in animals redu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shen, Kezhen, Feng, Xiaowen, Su, Rong, Xie, Haiyang, Zhou, Lin, Zheng, Shusen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425400/
https://ncbi.nlm.nih.gov/pubmed/25955525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126278
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