Melatonin ameliorates liver fibrosis induced by bile-duct ligation in rats

BACKGROUND: Hepatic stellate cells, the main mediators in the pathogenesis of fibrosis, are triggered by free radicals and produce collagen. Melatonin is a powerful physiologic scavenger of hydroxyl radicals. It is also involved in the inhibitory regulation of the collagen content in tissue. There i...

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Main Authors: Tahan, Gulgun, Akin, Hakan, Aydogan, Fatih, Ramadan, Saime Sezgin, Yapicier, Ozlem, Tarcin, Orhan, Uzun, Hafize, Tahan, Veysel, Zengin, Kagan
Formato: Artigo
Idioma:Inglês
Publicado: Canadian Medical Association 2010
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947113/
https://ncbi.nlm.nih.gov/pubmed/20858375
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