Dexamethasone inhibition of interleukin 1 beta production by human monocytes. Posttranscriptional mechanisms.

Dexamethasone is known to have an inhibitory effect on IL-1 production. To determine the mechanism(s) of this inhibition, adherent human blood monocytes were stimulated with Escherichia coli lipopolysaccharide (LPS) (10 micrograms/ml) in the presence of dexamethasone. Nuclear transcription run-off a...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Kern, J A, Lamb, R J, Reed, J C, Daniele, R P, Nowell, P C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442499/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3257219/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113301
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