Two distinct signaling pathways trigger the expression of inducible nitric oxide synthase in rat renal mesangial cells.

The expression of nitric oxide synthase (NOS; EC 1.14.13.39) is induced in rat glomerular mesangial cells by exposure to the inflammatory cytokine interleukin 1 beta (IL-1 beta) or cAMP-elevating agents. Stimulation with IL-1 beta alone leads to an approximately 40-fold increase in NOS activity and...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kunz, D, Mühl, H, Walker, G, Pfeilschifter, J
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC44000/
https://ncbi.nlm.nih.gov/pubmed/7515501
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