Two distinct signaling pathways trigger the expression of inducible nitric oxide synthase in rat renal mesangial cells.
The expression of nitric oxide synthase (NOS; EC 1.14.13.39) is induced in rat glomerular mesangial cells by exposure to the inflammatory cytokine interleukin 1 beta (IL-1 beta) or cAMP-elevating agents. Stimulation with IL-1 beta alone leads to an approximately 40-fold increase in NOS activity and...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1994
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44000/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7515501/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.12.5387 |
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