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PASTA: Ultra-Large Multiple Sequence Alignment for Nucleotide and Amino-Acid Sequences

We introduce PASTA, a new multiple sequence alignment algorithm. PASTA uses a new technique to produce an alignment given a guide tree that enables it to be both highly scalable and very accurate. We present a study on biological and simulated data with up to 200,000 sequences, showing that PASTA pr...

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Detalles Bibliográficos
Publicado en:J Comput Biol
Autores principales: Mirarab, Siavash, Nguyen, Nam, Guo, Sheng, Wang, Li-San, Kim, Junhyong, Warnow, Tandy
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424971/
https://ncbi.nlm.nih.gov/pubmed/25549288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2014.0156
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