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Ultra-large alignments using phylogeny-aware profiles

Many biological questions, including the estimation of deep evolutionary histories and the detection of remote homology between protein sequences, rely upon multiple sequence alignments and phylogenetic trees of large datasets. However, accurate large-scale multiple sequence alignment is very diffic...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Nguyen, Nam-phuong D., Mirarab, Siavash, Kumar, Keerthana, Warnow, Tandy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492008/
https://ncbi.nlm.nih.gov/pubmed/26076734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0688-z
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