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Identification of pneumococcal colonization determinants in the stringent response pathway facilitated by genomic diversity

BACKGROUND: Understanding genetic determinants of a microbial phenotype generally involves creating and comparing isogenic strains differing at the locus of interest, but the naturally existing genomic and phenotypic diversity of microbial populations has rarely been exploited. Here we report use of...

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Bibliografiska uppgifter
I publikationen:BMC Genomics
Huvudupphovsmän: Li, Yuan, Croucher, Nicholas J, Thompson, Claudette M, Trzciński, Krzysztof, Hanage, William P, Lipsitch, Marc
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424882/
https://ncbi.nlm.nih.gov/pubmed/25956132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1573-6
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