Prospective study of a molecular selection profile for RAS wild type colorectal cancer patients receiving irinotecan-cetuximab

BACKGROUND: The aim of our study was to evaluate whether a panel of biomarkers, prospectively analysed might be able to predict patients’ clinical outcome more accurately than RAS status alone. METHODS: K-RAS (exons 2, 3, 4) wild type colorectal cancer patients, candidates to second/third-line cetux...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Giampieri, Riccardo, Mandolesi, Alessandra, Abouelkhair, Khaled M, Loretelli, Cristian, Del Prete, Michela, Faloppi, Luca, Maristella, Bianconi, Ibrahim, Ezzeldin M, Scarpelli, Marina, Cascinu, Stefano, Scartozzi, Mario
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424481/
https://ncbi.nlm.nih.gov/pubmed/25943333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0501-5
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