Thymic expression of a T-cell receptor targeting a tumor-associated antigen coexpressed in the thymus induces T-ALL

T-cell receptors (TCRs) and chimeric antigen receptors recognizing tumor-associated antigens (TAAs) can now be engineered to be expressed on a wide array of immune effectors. Engineered receptors targeting TAAs have most commonly been expressed on mature T cells, however, some have postulated that r...

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Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Cui, Yongzhi, Onozawa, Masahiro, Garber, Haven R., Samsel, Leigh, Wang, Ziyao, McCoy, J. Philip, Burkett, Sandra, Wu, Xiaolin, Aplan, Peter D., Mackall, Crystal L.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2015
Sujets:
Lymphoid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424417/
https://ncbi.nlm.nih.gov/pubmed/25814528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-609271
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