Factor-induced Reprogramming and Zinc Finger Nuclease-aided Gene Targeting Cause Different Genome Instability in β-Thalassemia Induced Pluripotent Stem Cells (iPSCs)

The generation of personalized induced pluripotent stem cells (iPSCs) followed by targeted genome editing provides an opportunity for developing customized effective cellular therapies for genetic disorders. However, it is critical to ascertain whether edited iPSCs harbor unfavorable genomic variati...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ma, Ning, Shan, Yongli, Liao, Baojian, Kong, Guanyi, Wang, Cheng, Huang, Ke, Zhang, Hui, Cai, Xiujuan, Chen, Shubin, Pei, Duanqing, Chen, Nansheng, Pan, Guangjin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Genomics and Proteomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424344/
https://ncbi.nlm.nih.gov/pubmed/25795783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.624999
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados