Genetic Deficiency of Mtdh Gene in Mice Causes Male Infertility via Impaired Spermatogenesis and Alterations in the Expression of Small Non-coding RNAs

Increased expression of metadherin (MTDH, also known as AEG-1 and 3D3/LYRIC) has been associated with drug resistance, metastasis, and angiogenesis in a variety of cancers. However, the specific mechanisms through which MTDH is involved in these processes remain unclear. To uncover these mechanisms,...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Meng, Xiangbing, Yang, Shujie, Zhang, Yuping, Wang, Xinjun, Goodfellow, Renee X., Jia, Yichen, Thiel, Kristina W., Reyes, Henry D., Yang, Baoli, Leslie, Kimberly K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424326/
https://ncbi.nlm.nih.gov/pubmed/25787082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.627653
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