Palmitoylethanolamide Treatment Reduces Blood Pressure in Spontaneously Hypertensive Rats: Involvement of Cytochrome P450-Derived Eicosanoids and Renin Angiotensin System

Palmitoylethanolamide (PEA), a peroxisome proliferator-activated receptor-α agonist, has been demonstrated to reduce blood pressure and kidney damage secondary to hypertension in spontaneously hypertensive rat (SHR). Currently, no information is available concerning the putative effect of PEA on mod...

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Veröffentlicht in:PLoS One
Hauptverfasser: Mattace Raso, Giuseppina, Pirozzi, Claudio, d'Emmanuele di Villa Bianca, Roberta, Simeoli, Raffaele, Santoro, Anna, Lama, Adriano, Di Guida, Francesca, Russo, Roberto, De Caro, Carmen, Sorrentino, Raffaella, Calignano, Antonio, Meli, Rosaria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423982/
https://ncbi.nlm.nih.gov/pubmed/25951330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123602
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