An orally administered butyrate‐releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium‐induced murine colitis

BACKGROUND AND PURPOSE: Butyrate has shown benefits in inflammatory bowel diseases. However, it is not often administered orally because of its rancid smell and unpleasant taste. The efficacy of a more palatable butyrate‐releasing derivative, N‐(1‐carbamoyl‐2‐phenylethyl) butyramide (FBA), was evalu...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Simeoli, Raffaele, Mattace Raso, Giuseppina, Pirozzi, Claudio, Lama, Adriano, Santoro, Anna, Russo, Roberto, Montero‐Melendez, Trinidad, Berni Canani, Roberto, Calignano, Antonio, Perretti, Mauro, Meli, Rosaria
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Themed Section: Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429328/
https://ncbi.nlm.nih.gov/pubmed/27684049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13637
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