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In vivo regulation of human mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase. Decreased enzyme catalytic efficiency in familial hypercholesterolemia.

3-Hydroxy-3-methylglutaryl coenzyme A reductase (HMG CoA reductase) controls the rate of cholesterol biosynthesis and is itself modulated through feedback suppression by internalized low density lipoprotein (LDL) cholesterol. We measured HMG CoA reductase protein concentration and microsomal enzyme...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Stacpoole, P W, Bridge, D M, Alvarez, I M, Goldberg, R B, Harwood, H J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1987
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC442396/
https://ncbi.nlm.nih.gov/pubmed/2824560
Tagiau: Ychwanegu Tag
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