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The Autism Related Protein Contactin-Associated Protein-Like 2 (CNTNAP2) Stabilizes New Spines: An In Vivo Mouse Study

The establishment and maintenance of neuronal circuits depends on tight regulation of synaptic contacts. We hypothesized that CNTNAP2, a protein associated with autism, would play a key role in this process. Indeed, we found that new dendritic spines in mice lacking CNTNAP2 were formed at normal rat...

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Gdalyahu, Amos, Lazaro, Maria, Penagarikano, Olga, Golshani, Peyman, Trachtenberg, Joshua T., Gescwind, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423902/
https://ncbi.nlm.nih.gov/pubmed/25951243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125633
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