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Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism

Mouse models of neuropsychiatric diseases provide a platform for mechanistic understanding and development of new therapies. We previously demonstrated that knockout of the mouse homologue of CNTNAP2, in which mutant forms cause Cortical Dysplasia and Focal Epilepsy syndrome (CDFE), displays many fe...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Peñagarikano, Olga, Lázaro, María T., Lu, Xiao-Hong, Gordon, Aaron, Dong, Hongmei, Lam, Hoa A., Peles, Elior, Maidment, Nigel T., Murphy, Niall P., Yang, X. William, Golshani, Peyman, Geschwind, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498455/
https://ncbi.nlm.nih.gov/pubmed/25609168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3010257
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