Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism

Mouse models of neuropsychiatric diseases provide a platform for mechanistic understanding and development of new therapies. We previously demonstrated that knockout of the mouse homologue of CNTNAP2, in which mutant forms cause Cortical Dysplasia and Focal Epilepsy syndrome (CDFE), displays many fe...

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Gepubliceerd in:Sci Transl Med
Hoofdauteurs: Peñagarikano, Olga, Lázaro, María T., Lu, Xiao-Hong, Gordon, Aaron, Dong, Hongmei, Lam, Hoa A., Peles, Elior, Maidment, Nigel T., Murphy, Niall P., Yang, X. William, Golshani, Peyman, Geschwind, Daniel H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498455/
https://ncbi.nlm.nih.gov/pubmed/25609168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3010257
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