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Highly recurrent TERT promoter mutations in human melanoma
Sequencing studies have identified many recurrent coding mutations in human cancer genes; however, highly recurrent mutations involving regulatory regions have rarely been observed. Here we describe two independent mutations within the TERT core promoter that, when taken together, were observed in 7...
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| Veröffentlicht in: | Science |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4423787/ https://ncbi.nlm.nih.gov/pubmed/23348506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1229259 |
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