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Identification of Variants in Primary and Recurrent Glioblastoma Using a Cancer-Specific Gene Panel and Whole Exome Sequencing

Glioblastoma (GBM) is an aggressive, malignant brain tumor typically resulting in death of the patient within one year following diagnosis; and those who survive beyond this point usually present with tumor recurrence within two years (5-year survival is 5%). The genetic heterogeneity of GBM has mad...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Virk, Selene M., Gibson, Richard M., Quinones-Mateu, Miguel E., Barnholtz-Sloan, Jill S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423782/
https://ncbi.nlm.nih.gov/pubmed/25950952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124178
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