Vascular Permeability during Antiangiogenesis Treatment: MR Imaging Assay Results as Biomarker for Subsequent Tumor Growth in Rats(1)

Purpose: To prospectively evaluate in rats the acute change in tumor vascular leakiness (K(PS)) assayed at magnetic resonance (MR) imaging after a single dose of the angiogenesis inhibitor bevacizumab as a predictive biomarker of tumor growth response after a prolonged treatment course. Materials an...

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Bibliographic Details
Published in:Radiology
Main Authors: Raatschen, Hans-Juergen, Simon, Gerhard H., Fu, Yanjun, Sennino, Barbara, Shames, David M., Wendland, Michael F., McDonald, Donald M., Brasch, Robert C.
Format: Artigo
Language:Inglês
Published: Radiological Society of North America 2008
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423757/
https://ncbi.nlm.nih.gov/pubmed/18372448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.2472070363
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